ACGT Master Ontology (MO)
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|You can download the newest working version of ACGT MO from the link below.||You can download the newest working version of ACGT MO from the link below.|
|== Comments, Submission and Contact ==||== Comments, Submission and Contact ==|
Revision as of 13:30, 15 July 2009
For general information on the EU-funded project "Advancing Clinico-Genomic Trials on Cancer" (ACGT) go here. 
The intention of the ACGT Master Ontology (MO) is to represent the domain of cancer research and management in a computationally tractable manner. The ACGT MO is built being maintained, using the Protégé-OWL free open-source ontology editor, Version 4 . It is written in OWL-DL  and presented as an .owl file. The ACGT MO is re-using Basic Formal Ontology (BFO)  as upper level and the OBO Relation Ontology .
You can download the newest working version of ACGT MO from the link below.
Comments, Submission and Contact
The developers of the ACGT MO and the ACGT Consortium encourage comments and submissions to optimize and extend ACGT MO. If you have comments or questions or comments concerning the ACGT MO or if you want to submit proposals fur further classes, please contact one of the curators:
Dr. Mathias Brochhausen: firstname.lastname@example.org
Cristian Cocos PhD: email@example.com
The ACGT Consortium aims to set up a maintenance system. Details on the development can be found under "Documentation".
The Basic Formal Ontology (BFO) Manual by A. D. Spears 
Training Course: An Introduction in Biomedical Ontologies by B. Smith. Streaming Video. 
Brochhausen M, Weiler G, Martin L, Cocos C, Stenzhorn H, Graf N, Dörr M, Tsiknakis M, Smith B, "Applications of the ACGT Master Ontology on Cancer," In: R. Meersman, Z. Tari, P. Herrero (eds.): OTM 2008 Workshops, LNCS 5333, 2008, 1046-1055.
Brochhausen M, Weiler G, Cocos C, Stenzhorn H, Graf N, Doerr M, Tsiknakis M, “The ACGT Master Ontology on Cancer - a New Terminology Source for Oncological Practice,” In: Puuronen S, Pechenizkiy M, Tsymbal A, Lee DJ (eds.): Proceedings of the 21st IEEE International Symposium on Computer-Based Medical Systems, 2008, IEEE Computer Society, Los Alamitos, 324-329.
Smith B, Brochhausen M, "Establishing and Harmonizing Ontologies in an Interdisciplinary Health Care and Clinical Research Environment". Health, Technology and Informatics, 134, 2008, 219-234. 
Tsiknakis M, Brochhausen M, Nabrzyski J, Pucaski J, Potamias G, Desmedt C, Kafetzopoulos D, “A semantic grid infrastructure enabling integrated access and analysis of multilevel biomedical data in support of post-genomic clinical trials on Cancer”, IEEE Transactions on Information Technology in Biomedicine, Special issue on Bio-Grids, 2008, Vol. 12, No. 2, pp. 205-217.
Weiler G, Brochhausen M, Graf N, Hoppe A, Schera F, Kiefer S, "Ontology Based Data Management Systems for post-genomic clinical Trials within an European Grid Infrastructure for Cancer Research", In: Proc of the 29th Annual International Conference of the IEEE EMBS, Lyon, France, August 23-26, 2007, pp. 6434-6437.