Schloss Dagstuhl · 20-23 June 2007



Reasoning with Biomedical Information:

Training Course in Logic for Biomedical Research

 

Program

 


 

 

Organized by Barry Smith in collaboration with

·         European Network of Excellence SemanticMining,

·         NCBO – US National Center for Biomedical Ontology,

·         RIDE – A Roadmap for Interoperability of eHealth Systems,

·         ECOR – European Centre for Ontological Research,

·         ACGT – EU 'Integrated Project' Advancing Clinico-Genomic Trials on Cancer,

·         IFOMIS – Institute for Formal Ontology and Medical Information Science.
 

This three-day training course is designed to provide a basic introduction to the field of biomedical ontology and to enhance awareness of current developments and best practices in ontology in the life sciences, focusing on logical and computational aspects. It will feature a special debate on the future of OWL DL in biomedical ontology development.

 

Intended Audience

Overview

Program

Adminstrative

Faculty

 

 

Intended Audience

 

Attendees who might find this training course worthwhile include:

·         developers and users of biomedical ontologies, terminologies and coding systems,

·         developers and users of electronic patient record systems,

·         biologists and physicians interested in the possibilities of modern ontologies.

We are targeting advanced doctoral students, but welcome interested post-doc and industrial participants as well. The number of participants is restricted to about 30 to maximize possibilities for intense discussion.

 

Overview

 

Barry Smith: Introduction to Terminology, Ontology, and the Philosophy of Language for Biomedical Researchers

 

 

Deborah McGuinness: The Future of the Semantic Web

 

 

Fabian Neuhaus: Introduction to Logic and Semantics for Biomedical Researchers

 

 

Alan Rector: Introduction to Programming with OWL and Its Problems

 

 

Nigam Shah: Introduction to OWL and its Alternatives for Biomedical Researchers & Varieties of Reasoning

 

 

Program

 

Administration

 

Participants should plan to arrive in Dagstuhl in the morning of Wednesday, June 20, 2007. The program will begin after lunch and conclude on Saturday morning, June 23, with breakfast, the last plenary session finishing Friday, 6 pm.

The registration fee is € 600 and includes lodging and full board at Schloss Dagstuhl. A non-refundable registration fee of € 20 is included in this amount. Doctoral students and other academics may apply for a grant of up to €400 to assist their participation.

Further details on the amenities at Dagstuhl and getting there may be found here.

Inquiries about the course and registration should be addressed to michelle.carnell@ifomis.uni-saarland.de.

 

 

Faculty

 

Barry Smith

 

Barry Smith is Julian Park Distinguished Professor of Philosophy in the University at Buffalo (New York, USA) and Director of the Institute for Formal Ontology and Medical Information Science in Saarbrücken, Germany. He is the author of some 400 scientific publications, including 15 authored or edited books, and editor of The Monist: An International Quarterly Journal of General Philosophical Inquiry. His research has been funded by the US, Swiss and Austrian National Science Foundations, the Volkswagen Foundation, and the European Union. In 2002 he received in recognition of his scientific achievements the 2.2 Million Euro Wolfgang Paul Award of the Alexander von Humboldt Foundation. In collaboration with the IFOMIS, the OBO (Open Biomedical Ontologies), FMA (Foundational Model of Anatomy), and the GALEN research groups, he developed a consensus approach to the construction of ontologies and terminologies in biomedicine. The methodology is now codified as the OBO Relations Ontology (http://obo.sourceforge.net/relationship) and serves as the basis for the OBO Foundry project (http://obofoundry.org), a collaborative effort of the world’s leading groups in biomedical ontology development that provides biomedical research groups with a library of gold standard reference ontologies. Together with Michael Ashburner FRS (Professor of Genetics, Cambridge University), and Suzanna Lewis (Director of Berkeley Drosophila Genome Project) Barry Smith has been named custodian of the OBO Foundry (http://obofoundry.buffalo.edu).

 

 

Deborah McGuinness

 

Deborah McGuinness is the acting director and senior research scientist at the Knowledge Systems, (KSL) Artificial Intelligence Laboratory at Stanford University. She is a leading expert in knowledge representation and reasoning languages and systems and has worked in ontology creation and evolution environments for over 20 years. Most recently, Deborah is best known for her leadership role in semantic web research, and for her work on explanation, trust, and applications of semantic web technology, particularly for scientific applications. Deborah is co-editor of the Ontology Web Language which has emerged from web ontology working group of the World Wide Web (W3C) semantic web activity and has now achieved W3C Recommendation status. She helped start the web ontology working group out of work as a co-author of the DARPA Agent Markup Language program's DAML language. She helped form the Joint EU/US Agent Markup Language Committee which evolved the DAML language into the DAML+OIL description logic-based ontology language. She is a co-author of one of the more widely used long-lived description logic systems (CLASSIC) from Bell Laboratories. Her work on languages (including OWL, DAML+OIL, OIL, CLASSIC, etc.) is aimed at providing languages that enable the next generation of web applications moving from a web aimed at human consumption to the semantic web aimed at machine consumption in support of intelligent assistants and web agents. Deborah is a leader in ontology-based tools and applications. She is a co-author and technical leader of the Stanford KSL ontology evolution environment. She also consulted to help VerticalNet design and build its Ontobuilder/Ontoserver ontology evolution environment. She also provided technical leadership for the Stanford project to help Cisco systems form its ontology evolution plan for its meta data formation work.

 

 

Fabian Neuhaus

 

Fabian Neuhaus is a postdoctoral fellow at the University at Buffalo.

 

 

Alan Rector

 

Alan Rector is Professor of Medical Informatics in the Department of Computer Science at University of Manchester. He received his BA in Philosophy and Mathematics from Pomona College, his medical training at the universities of Chicago and Minnesota where he obtained his MD, and his PhD in Medical Informatics from the University of Manchester.

Over the past twenty-five years he has led a series of projects on clinical decision support, medical records, and medical terminology including the ground breaking PEN&PAD project on intelligent medical records sponsored jointly by the UK Medical Research Council and Department of Health.

During the 1990s his work focused on medical terminology and ontologies, and he led the EU sponsored GALEN programme (www.opengalen.org) and the UK Drug Ontology project sponsored by the Department of Health in conjunction with the Prodigy Programme for decision support in prescribing in general practice.

Since 2002 he has led the MRC sponsored Cooperative Clinical E-Science Framework (CLEF) consortium of seven UK universities, NHS trusts, and Cancer Networks which aims to provide "joined up" information solutions for clinical care and clinical and bioscience research in cancer. >From 2003 he leads the JISC and EPSRC funded Co-ODE and HyOntUse projects, working with Stanford University and Epistemics to create a new platform for cooperative ontology development.

His work on clinical terminology and ontologies provided a key stimulus for the technologies underpinning the use of ontologies for the Semantic Web. He has been a visiting senior scientist at Stanford University and consultant to the NHS Information Authority, Hewlett Packard, the Mayo Clinic, and a variety of smaller companies. He is a member of the JISC Committee for the Support of Research, the National Cancer Research Institute Board for Bioinformatics, the Joint NHS/Higher Education Forum on Informatics, and the Board of the Academic Forum of the UK Institute for Health Informatics. He is also active in HL7, the main standards body for health informatics, and on the board of HL7-UK.

He currently leads the CO-ODE and HyOntUse projects developing user oriented ontology development environments under the JISC and EPSRC Semantic Web and Autonomic Computing initiatives as well as the CLEF project, developing secure and ethical methods to collect live patient record data in research repositories, under the MRC eScience initiative.

 

 

Nigam Shah

 

Nigam Shah is a postdoctoral fellow with the National Center for Biomedical Ontology. He received his MBBS degree from M.S. University in India followed by a PhD in Integrative Biosciences from Penn State University. His thesis work was focused on developing formal methods for the representation, manipulation and integration of diverse biological data - such as gene expression, protein interactions & annotations - with prior biological knowledge for the purpose of evaluating alternative hypotheses. The prototype system is available at www.hybrow.org.
He has conducted tutorials on 'How to make and use ontologies in biomedicine' and lectures on the 'Uses of ontologies' in BMI courses at Stanford. His current research is focused on developing ontology-based reasoning applications in the biomedical sciences.